IL16 and KCNJ4

Number of citations of the paper that reports this interaction (PubMedID 10479680)
20

Data Source:
HPRD (two hybrid)

		IL16	KCNJ4
Description		interleukin 16	potassium inwardly rectifying channel subfamily J member 4
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Nuclear Speck Flemming Body	Plasma Membrane Voltage-gated Potassium Channel Complex Basolateral Plasma Membrane Cell Junction Cytoplasmic Vesicle Membrane Postsynaptic Membrane
	Molecular Function	Cytokine Activity CD4 Receptor Binding	Inward Rectifier Potassium Channel Activity Protein Binding PDZ Domain Binding
	Biological Process	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		Other interleukin signaling	Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Carvedilol
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Primary biliary cholangitis ( 28425483)	Automobile speeding propensity ( 30643258) Chronotype ( 30696823) Conotruncal heart defects ( 24800985)
Interacting Genes		31 interacting genes: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A LNX2 PCSK6 PPP1R12A PPP1R12B PPP1R12C SUV39H1 TFIP11 TRIP6 USHBP1 ZNRD2	10 interacting genes: CASK DLG1 DLG2 DLG4 GNGT2 IL16 KCNJ2 LIN7B PRKCD SNTA1
Entrez ID		3603	3761
HPRD ID		04329	02738
Ensembl ID		ENSG00000172349	ENSG00000168135
Uniprot IDs		Q14005 Q9UME6	A0A024R1L8 P48050 Q58F07
PDB IDs		1I16 1X6D 5FB8	3GJ9
Enriched GO Terms of Interacting Partners?
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