IL16 and KCND2

Number of citations of the paper that reports this interaction (PubMedID 10479680)
20

Data Source:
HPRD (two hybrid)

		IL16	KCND2
Description		interleukin 16	potassium voltage-gated channel subfamily D member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Nuclear Speck Flemming Body	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Postsynaptic Density Integral Component Of Membrane Cell Junction Dendrite Intrinsic Component Of Plasma Membrane Neuronal Cell Body Membrane Dendritic Spine Perikaryon Plasma Membrane Raft Postsynaptic Membrane Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Cytokine Activity CD4 Receptor Binding	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Protein Binding Metal Ion Binding Voltage-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport	Action Potential Chemical Synaptic Transmission Neuronal Action Potential Sensory Perception Of Pain Regulation Of Ion Transmembrane Transport Locomotor Rhythm Protein Homooligomerization Regulation Of Postsynaptic Membrane Potential Cardiac Conduction Cellular Response To Hypoxia Potassium Ion Transmembrane Transport
Pathways		Other interleukin signaling	Voltage gated Potassium channels Phase 1 - inactivation of fast Na+ channels
Drugs			Disopyramide Amitriptyline Imipramine Dalfampridine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Primary biliary cholangitis ( 28425483)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Alcohol and nicotine co-dependence ( 22488850) Heel bone mineral density ( 30598549) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		31 interacting genes: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A LNX2 PCSK6 PPP1R12A PPP1R12B PPP1R12C SUV39H1 TFIP11 TRIP6 USHBP1 ZNRD2	8 interacting genes: DLG4 DPP10 FLNC IL16 KCNIP1 KCNIP2 KCNIP4 NCS1
Entrez ID		3603	3751
HPRD ID		04329	09254
Ensembl ID		ENSG00000172349	ENSG00000184408
Uniprot IDs		Q14005 Q9UME6	A4D0V9 Q9NZV8
PDB IDs		1I16 1X6D 5FB8
Enriched GO Terms of Interacting Partners?
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