TBC1D10C and HOXA1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TBC1D10C	HOXA1
Description		TBC1 domain family member 10C	homeobox A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Filopodium Membrane Ficolin-1-rich Granule Membrane	Nuclear Chromatin
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Intracellular Protein Transport Retrograde Transport, Endosome To Golgi Neutrophil Degranulation Negative Regulation Of B Cell Activation Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Calcineurin-NFAT Signaling Cascade Activation Of GTPase Activity Regulation Of Cilium Assembly	Multicellular Organism Development Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis
Pathways		Neutrophil degranulation TBC/RABGAPs	Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases			Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)
Interacting Genes		7 interacting genes: APP HOXA1 KLHL12 KRTAP13-1 KRTAP5-9 NOTCH2NLA PPP3R2	62 interacting genes: ADAMTSL4 ALG13 BLZF1 CCDC33 CHIC2 CHRD DUSP22 EFEMP2 GATA1 GP9 GRN KDM1A KRT31 KRT38 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NLA PBX2 PIK3R1 PKNOX1 PLSCR1 PRMT6 RBCK1 RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAF2 TRAPPC6A TRIM42 TRIP6
Entrez ID		374403	3198
HPRD ID		13330	00843
Ensembl ID		ENSG00000175463	ENSG00000105991
Uniprot IDs		Q8IV04	P49639
PDB IDs
Enriched GO Terms of Interacting Partners?
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