ITGB8 and TGFB1

  • Number of citations of the paper that reports this interaction (PubMedID 11970960)
  • 260
  • Data Source:
  • HPRD (in vitro, in vivo)

ITGB8

TGFB1

Description integrin subunit beta 8 transforming growth factor beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 31361310 30929738 31619474)
  • Asthma (childhood onset) ( 30929738)
  • Asthma onset (childhood vs adult) ( 30929738)
  • Asthma or allergic disease (pleiotropy) ( 29785011)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Eosinophil counts ( 29403010)
  • Inflammatory bowel disease ( 28067908)
  • Medication use (adrenergics, inhalants) ( 31015401)
  • Metabolite levels ( 23823483)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Prostate cancer ( 29892016)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
  • Blood protein levels ( 30072576)
  • Colorectal cancer ( 27145994 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Coronary artery disease ( 29212778 28714974)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Hematuria ( 30476138)
  • Hematuria (mild) ( 30476138)
  • Hematuria (moderate to severe) ( 30476138)
  • Preterm birth (maternal effect) ( 28877031)
  • Pulse pressure ( 30578418)
  • Type 2 diabetes ( 31049640)
Interacting Genes 3 interacting genes: ITGAV TGFB1 VTN 59 interacting genes: ACVRL1 AGR3 ANGPTL4 APP BCAS3 BGN BLID BMP2 BMP3 CCDC33 CCL3 CCL5 CCN2 COL2A1 CST6 DAXX DCN DIRAS3 DPT EIF3I ENG FCN1 FKBP1A FMOD FNTA GREB1 HOXC6 ITGAV ITGB6 ITGB8 KLK5 KLK7 KLK9 LAMTOR5 LTBP1 LTBP3 LTBP4 MEOX2 MMP2 MTA3 NSD3 PDLIM2 PRSS50 PSMC3IP PZP SCGB3A1 SDC2 SNAI1 SPARC ST14 TGFB2 TGFBR1 TGFBR2 TGFBR3 THBS1 THRSP VASN VTN YWHAE
Entrez ID 3696 7040
HPRD ID 05001 01821
Ensembl ID ENSG00000105855 ENSG00000105329
Uniprot IDs P26012 Q9BUG9 A0A499FJK2 P01137
PDB IDs 6DJP 1KLA 1KLC 1KLD 3KFD 4KV5 5FFO 5VQP
Enriched GO Terms of Interacting Partners?
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