ITGAV and ITGB8

  • Number of citations of the paper that reports this interaction (PubMedID 1918072)
  • 44
  • Data Source:
  • HPRD (in vivo)

ITGAV

ITGB8

Description integrin subunit alpha V integrin subunit beta 8
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Lung function (FEV1/FVC) ( 30804560)
  • Microalbuminuria ( 26631737)
  • Urinary albumin-to-creatinine ratio ( 26631737)
  • Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 31361310 30929738 31619474)
  • Asthma (childhood onset) ( 30929738)
  • Asthma onset (childhood vs adult) ( 30929738)
  • Asthma or allergic disease (pleiotropy) ( 29785011)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Eosinophil counts ( 29403010)
  • Inflammatory bowel disease ( 28067908)
  • Medication use (adrenergics, inhalants) ( 31015401)
  • Metabolite levels ( 23823483)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Prostate cancer ( 29892016)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes 33 interacting genes: ADAM9 ANGPTL3 AUP1 AZGP1 CALR CCN1 CCN3 CD47 EDIL3 F2R ICAM4 ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 L1CAM LGALS3BP MAPK3 MMP14 MMP2 NID1 P2RY2 PAK4 PDGFRA PLA2G2A PLP1 PTK2 PXN SPP1 TGFB1 THY1 UBC 3 interacting genes: ITGAV TGFB1 VTN
Entrez ID 3685 3696
HPRD ID 01903 05001
Ensembl ID ENSG00000138448 ENSG00000105855
Uniprot IDs L7RXH0 P06756 P26012 Q9BUG9
PDB IDs 1JV2 1L5G 1M1X 1U8C 3IJE 4G1E 4G1M 4MMX 4MMY 4MMZ 4O02 4UM8 4UM9 5FFG 5FFO 5NEM 5NER 5NET 5NEU 6AVQ 6AVR 6AVU 6DJP 6MK0 6MSL 6MSU 6DJP
Enriched GO Terms of Interacting Partners?
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