ITGAV and ITGB3

  • Number of citations of the paper that reports this interaction (PubMedID 11884718)
  • 397
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

ITGAV

ITGB3

Description integrin subunit alpha V integrin subunit beta 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Lung function (FEV1/FVC) ( 30804560)
  • Microalbuminuria ( 26631737)
  • Urinary albumin-to-creatinine ratio ( 26631737)
  • Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
  • Body mass index ( 25673413)
  • Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183)
  • High chromosomal aberration frequency (chromosome type) ( 31586183)
  • Mean platelet volume ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 33 interacting genes: ADAM9 ANGPTL3 AUP1 AZGP1 CALR CCN1 CCN3 CD47 EDIL3 F2R ICAM4 ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 L1CAM LGALS3BP MAPK3 MMP14 MMP2 NID1 P2RY2 PAK4 PDGFRA PLA2G2A PLP1 PTK2 PXN SPP1 TGFB1 THY1 UBC 49 interacting genes: AKT1 ANGPTL3 APP CAPN1 CD36 CDK1 COL1A2 DAB1 DAB2 DOK1 EPS8 FBLN2 FGA FGFR1 FGG FLNA FLNB FN1 GRIA2 HRAS ILK ITGA2B ITGA5 ITGAV ITGB3BP KDR MAPK3 NID1 NUMB P2RY2 P4HB PDGFRA PDGFRB PDK1 PDPK1 PECAM1 PLA2G2A PLA2G4A PTK2 PTK2B PXN SHC1 SRC TGM2 THBS1 THY1 TLN1 TNS2 VTN
Entrez ID 3685 3690
HPRD ID 01903 01428
Ensembl ID ENSG00000138448 ENSG00000259207
Uniprot IDs L7RXH0 P06756 P05106
PDB IDs 1JV2 1L5G 1M1X 1U8C 3IJE 4G1E 4G1M 4MMX 4MMY 4MMZ 4O02 4UM8 4UM9 5FFG 5FFO 5NEM 5NER 5NET 5NEU 6AVQ 6AVR 6AVU 6DJP 6MK0 6MSL 6MSU 1JV2 1KUP 1KUZ 1L5G 1M1X 1M8O 1MIZ 1MK7 1MK9 1RN0 1S4X 1TYE 1U8C 2INI 2K9J 2KNC 2KV9 2L1C 2L91 2LJD 2LJE 2LJF 2MTP 2N9Y 2Q6W 2RMZ 2RN0 2VC2 2VDK 2VDL 2VDM 2VDN 2VDO 2VDP 2VDQ 2VDR 3FCS 3FCU 3IJE 3NID 3NIF 3NIG 3T3M 3T3P 3ZDX 3ZDY 3ZDZ 3ZE0 3ZE1 3ZE2 4CAK 4G1E 4G1M 4MMX 4MMY 4MMZ 4O02 4Z7N 4Z7O 4Z7Q 5HDB 6AVQ 6AVR 6AVU 6BXB 6BXF 6BXJ 6CKB 6MK0 6MSL 6MSU
Enriched GO Terms of Interacting Partners?
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