ITGB3 and PDK1

  • Number of citations of the paper that reports this interaction (PubMedID 10896934)
  • 18
  • Data Source:
  • BioGRID (enzymatic study)

ITGB3

PDK1

Description integrin subunit beta 3 pyruvate dehydrogenase kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 25673413)
  • Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183)
  • High chromosomal aberration frequency (chromosome type) ( 31586183)
  • Mean platelet volume ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
  • Blood protein levels ( 28240269)
  • Erectile dysfunction in type 1 diabetes ( 22704111)
  • Fasting plasma glucose ( 25187374)
Interacting Genes 49 interacting genes: AKT1 ANGPTL3 APP CAPN1 CD36 CDK1 COL1A2 DAB1 DAB2 DOK1 EPS8 FBLN2 FGA FGFR1 FGG FLNA FLNB FN1 GRIA2 HRAS ILK ITGA2B ITGA5 ITGAV ITGB3BP KDR MAPK3 NID1 NUMB P2RY2 P4HB PDGFRA PDGFRB PDK1 PDPK1 PECAM1 PLA2G2A PLA2G4A PTK2 PTK2B PXN SHC1 SRC TGM2 THBS1 THY1 TLN1 TNS2 VTN 15 interacting genes: AKT1 COL6A1 DLAT FGFR1 ITGB3 KAT2B LAMTOR5 PDHA1 PDK2 PIK3CA RPS6KB1 SGK1 USP4 XRCC6 YWHAQ
Entrez ID 3690 5163
HPRD ID 01428 03954
Ensembl ID ENSG00000259207 ENSG00000152256
Uniprot IDs P05106 B7Z7N6 Q15118
PDB IDs 1JV2 1KUP 1KUZ 1L5G 1M1X 1M8O 1MIZ 1MK7 1MK9 1RN0 1S4X 1TYE 1U8C 2INI 2K9J 2KNC 2KV9 2L1C 2L91 2LJD 2LJE 2LJF 2MTP 2N9Y 2Q6W 2RMZ 2RN0 2VC2 2VDK 2VDL 2VDM 2VDN 2VDO 2VDP 2VDQ 2VDR 3FCS 3FCU 3IJE 3NID 3NIF 3NIG 3T3M 3T3P 3ZDX 3ZDY 3ZDZ 3ZE0 3ZE1 3ZE2 4CAK 4G1E 4G1M 4MMX 4MMY 4MMZ 4O02 4Z7N 4Z7O 4Z7Q 5HDB 6AVQ 6AVR 6AVU 6BXB 6BXF 6BXJ 6CKB 6MK0 6MSL 6MSU 2Q8F 2Q8G 2Q8H
Enriched GO Terms of Interacting Partners?
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