IMPDH1 and HTRA1

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 75
  • Data Source:
  • BioGRID (two hybrid)

IMPDH1

HTRA1

Description inosine monophosphate dehydrogenase 1 HtrA serine peptidase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 22694956 23326517 23455636 23536807 20861866 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (CNV vs. GA) ( 22705344)
  • Age-related macular degeneration (extreme sampling) ( 23577725)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Age-related macular degeneration (wet) ( 17053108)
  • Coronary artery disease ( 29212778)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
  • Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
  • Diverticular disease ( 30177863)
  • Exudative age-related macular degeneration ( 25629512)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lung function (FEV1/FVC) ( 30061609 30804560)
  • Migraine ( 27322543)
  • Neovascular age-related macular degeneration ( 28703135)
  • Stroke ( 29531354)
  • Systolic blood pressure ( 30224653 30578418)
Interacting Genes 2 interacting genes: GMNN HTRA1 21 interacting genes: APOE BMP4 CAST CDYL COL1A1 COL2A1 COL3A1 COX5A CSNK2B FAM107A FCHSD2 GDF5 GOLGA2 IMPDH1 LRP10 MAPT NOS3 PARD6B RPS6KA1 TENT5A XIAP
Entrez ID 3614 5654
HPRD ID 08853 03725
Ensembl ID ENSG00000106348 ENSG00000166033
Uniprot IDs B3KRZ3 P20839 Q6ZNB1 Q92743
PDB IDs 1JCN 2JOA 2YTW 3NUM 3NWU 3NZI 3TJN 3TJO 3TJQ
Enriched GO Terms of Interacting Partners?
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