IK and THOC1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		IK	THOC1
Description		IK cytokine	THO complex 1
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GO Annotations	Cellular Component	Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Mitotic Spindle Pole	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Binding Identical Protein Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Mitotic Spindle Assembly Checkpoint Viral Process Protein Localization To Kinetochore	Regulation Of DNA Recombination RNA Processing RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA 3'-end Processing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Schizophrenia ( 29483656)	Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799)
Interacting Genes		19 interacting genes: APP CEP70 CHD3 CTNNBL1 FANCC FRA10AC1 GRB2 KAT5 KDM1A MFAP1 NUP62 PFN2 RACK1 RBM10 SUPT5H THOC1 TOE1 TTC14 ZCCHC10	14 interacting genes: ATP1B1 DHX8 FRA10AC1 IK MOAP1 MTNR1B NEDD4 RABGEF1 RB1 SAP30BP SF3B2 TRIM54 USHBP1 WDR77
Entrez ID		3550	9984
HPRD ID		02771	09498
Ensembl ID		ENSG00000113141	ENSG00000079134
Uniprot IDs		Q13123 Q95HA6 Q9UK43	Q96FV9
PDB IDs		5O9Z 6Q8I	1WXP
Enriched GO Terms of Interacting Partners?
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