THOC1 and MOAP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		THOC1	MOAP1
Description		THO complex 1	modulator of apoptosis 1
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Regulation Of DNA Recombination RNA Processing RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA 3'-end Processing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint	Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799)	Body mass index ( 26426971) Endometriosis ( 23472165) Migraine ( 27182965)
Interacting Genes		14 interacting genes: ATP1B1 DHX8 FRA10AC1 IK MOAP1 MTNR1B NEDD4 RABGEF1 RB1 SAP30BP SF3B2 TRIM54 USHBP1 WDR77	18 interacting genes: BAX BCL2 BCL2L1 CACNA1A CAMK2D CCDC85B DPPA2 FZR1 LATS1 MAGEH1 MBIP PNMA5 RASSF1 THOC1 TNFRSF10A TNFRSF1A UBQLN4 UBR5
Entrez ID		9984	64112
HPRD ID		09498	17580
Ensembl ID		ENSG00000079134	ENSG00000165943
Uniprot IDs		Q96FV9	Q96BY2
PDB IDs		1WXP
Enriched GO Terms of Interacting Partners?
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