APCS and COL4A1

  • Number of citations of the paper that reports this interaction (PubMedID 8662978)
  • 5
  • Data Source:
  • HPRD (in vitro)

APCS

COL4A1

Description amyloid P component, serum collagen type IV alpha 1 chain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related nuclear cataracts ( 24951543)
  • Arterial stiffness ( 20031579)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Coronary artery disease ( 29212778 24262325 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136)
  • Intraocular pressure ( 29785010 31959993)
  • Lateral ventricle volume ( 31530798)
  • Metabolite levels ( 23823483)
  • Monocyte count ( 27863252)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Obesity-related traits ( 23251661)
  • Peripheral artery disease ( 31285632)
  • Pulse pressure ( 30578418)
  • Stroke ( 30383316 29531354)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 17 interacting genes: C1QA C4BPA CALU COL4A1 COPS5 CRP FCGR1A FCGR2B FCGR3A FCGR3B FN1 GK GOT2 GRB2 HES1 LAMA1 TG 27 interacting genes: ACHE APCS APP BMP3 CD93 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI THBS1
Entrez ID 325 1282
HPRD ID 00101 00359
Ensembl ID ENSG00000132703 ENSG00000187498
Uniprot IDs P02743 V9HWP0 A5PKV2 P02462
PDB IDs 1GYK 1LGN 1SAC 2A3W 2A3X 2A3Y 2W08 3D5O 3KQR 4AVS 4AVT 4AVV 4AYU 1LI1 5NAX 5NAY 6MPX
Enriched GO Terms of Interacting Partners?
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