COL4A1 and THBS1

  • Number of citations of the paper that reports this interaction (PubMedID 3571333)
  • 39

COL4A1

THBS1

Description collagen type IV alpha 1 chain thrombospondin 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age-related nuclear cataracts ( 24951543)
  • Arterial stiffness ( 20031579)
  • Behavioral disturbance or psychiatric symptoms and prion disease ( 25897833)
  • Coronary artery disease ( 29212778 24262325 30104761 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)
  • Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) ( 30920136)
  • Intraocular pressure ( 29785010 31959993)
  • Lateral ventricle volume ( 31530798)
  • Metabolite levels ( 23823483)
  • Monocyte count ( 27863252)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Obesity-related traits ( 23251661)
  • Peripheral artery disease ( 31285632)
  • Pulse pressure ( 30578418)
  • Stroke ( 30383316 29531354)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
  • Logical memory (immediate recall) in normal cognition ( 29274321)
  • Urate levels ( 31578528)
Interacting Genes 27 interacting genes: ACHE APCS APP BMP3 CD93 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI THBS1 40 interacting genes: CALCR CALR CD36 CD47 CFH COL1A1 COL2A1 COL3A1 COL4A1 COL5A1 COL7A1 CORO1A CTSG DCN DHFR ELANE F2 FGA FGF2 FN1 HRG IGFBP5 ITGB3 JAG1 KNG1 LAMB3 LRP1 LRP2 LRP5 MMP2 MMP9 MTDH PDGFB PLG SCARB2 SPARC TFPI TGFB1 TNFAIP6 TNFRSF11B
Entrez ID 1282 7057
HPRD ID 00359 01765
Ensembl ID ENSG00000187498 ENSG00000137801
Uniprot IDs A5PKV2 P02462 P07996
PDB IDs 1LI1 5NAX 5NAY 6MPX 1LSL 1UX6 1Z78 1ZA4 2ERF 2ES3 2OUH 2OUJ 3R6B 5FOE
Enriched GO Terms of Interacting Partners?
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