HBG2 and RPSA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HBG2	RPSA
Description		hemoglobin subunit gamma 2	ribosomal protein SA
Image
GO Annotations	Cellular Component	Cytosol Hemoglobin Complex Haptoglobin-hemoglobin Complex Blood Microparticle	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Oxygen Binding Heme Binding Haptoglobin Binding Hemoglobin Alpha Binding Organic Acid Binding Metal Ion Binding	Virus Receptor Activity RNA Binding Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding
	Biological Process	Blood Coagulation Oxygen Transport Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Viral Transcription Viral Entry Into Host Cell
Pathways		Factors involved in megakaryocyte development and platelet production	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Tigapotide Copper
Diseases
GWAS		Beta thalassemia/hemoglobin E disease ( 20183929) Hemoglobin ( 28548082) Hemoglobin levels ( 26366553) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Malate levels ( 31560688) Mean corpuscular hemoglobin concentration ( 28453575) Red cell distribution width ( 27863252)	Dentate gyrus volume x schizophrenia interaction ( 31155012)
Interacting Genes		5 interacting genes: APP CYB5R3 HBB RPSA SMAD5	28 interacting genes: ABCD1 ACADVL ACD ANKH CALM2 CBX5 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD HSPB1 IL7R ILRUN ITGA6 KARS1 LAMA2 NKX3-1 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3
Entrez ID		3048	3921
HPRD ID		00792	01038
Ensembl ID		ENSG00000196565	ENSG00000168028
Uniprot IDs		D9YZU9 P69892	A0A024R2L6 A0A0C4DG17 P08865
PDB IDs		1FDH 4MQJ 4MQK	3BCH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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