SLC40A1 and GOLM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		SLC40A1	GOLM1
Description		solute carrier family 40 member 1	golgi membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleoplasm Cytoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Basolateral Plasma Membrane	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Plasma Membrane
	Molecular Function	Iron Ion Transmembrane Transporter Activity Protein Binding Ferrous Iron Transmembrane Transporter Activity Peptide Hormone Binding Identical Protein Binding	Protein Binding
	Biological Process	Lymphocyte Homeostasis Endothelium Development Cellular Iron Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Iron Ion Transmembrane Transport Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Iron Ion Homeostasis Spleen Trabecula Formation Multicellular Organismal Iron Ion Homeostasis Divalent Inorganic Cation Transport Ferrous Iron Export Across Plasma Membrane	Nucleus Organization Regulation Of Lipid Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Metal ion SLC transporters Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) Defective CP causes aceruloplasminemia (ACERULOP) Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) Iron uptake and transport	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases		Hemochromatosis (HFE); Juvenile hemochromatosis (JH)
GWAS		Bone fracture in osteoporosis ( 28580392) Iron status biomarkers (ferritin levels) ( 25352340) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin levels) ( 25352340) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Red blood cell count ( 27863252)	Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		2 interacting genes: GOLM1 HAMP	27 interacting genes: B3GNT4 C1orf174 CIAO1 CLK1 DCK DCTN2 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 GEMIN7 GRIK5 KCNE3 LSM12 MED22 NIPSNAP3A NRSN2 RACK1 RPA2 RPL13A SLC40A1 SYT1 TLE1 ZFAND3
Entrez ID		30061	51280
HPRD ID		05229	08428
Ensembl ID		ENSG00000138449	ENSG00000135052
Uniprot IDs		Q9NP59	B3KNK9 Q8NBJ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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