H1-2 and PUF60

Number of citations of the paper that reports this interaction (PubMedID 18258596)
47

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		H1-2	PUF60
Description		H1.2 linker histone, cluster member	poly(U) binding splicing factor 60
Image		No pdb structure
GO Annotations	Cellular Component	Nucleosome Nuclear Chromatin Nucleus Nuclear Euchromatin Transcriptionally Active Chromatin	Nucleoplasm Cell Junction
	Molecular Function	Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding	DNA Binding RNA Binding Protein Binding Identical Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Nucleosome Assembly Regulation Of Transcription, DNA-templated Nucleosome Positioning Chromosome Condensation Negative Regulation Of Chromatin Silencing Negative Regulation Of DNA Recombination Histone H3-K4 Trimethylation Histone H3-K27 Trimethylation	MRNA Splicing, Via Spliceosome Apoptotic Process
Pathways		Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		30 interacting genes: AEBP2 APP ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 RBM39 SNCA VHL WDR12 WDR5 YBX1	34 interacting genes: ARL8A BORCS5 CACNA1A CCNC CD101 CHD3 CPEB2 ERG FBXO7 FHL2 FUBP1 H1-2 ID3 IQCN KHDC4 LARP7 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B RAP1GDS1 SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16
Entrez ID		3006	22827
HPRD ID		07514	18051
Ensembl ID		ENSG00000187837	ENSG00000179950
Uniprot IDs		P16403	Q9UHX1
PDB IDs			2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT 5KVY 5KW1 5KW6 5KWQ
Enriched GO Terms of Interacting Partners?
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