SH3GLB1 and EXOSC5

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		SH3GLB1	EXOSC5
Description		SH3 domain containing GRB2 like, endophilin B1	exosome component 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex	Nuclear Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) Exosome (RNase Complex) Nucleoplasm Nucleolus Cytoplasm Cytosol Transcriptionally Active Chromatin
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding	3'-5'-exoribonuclease Activity RNA Binding Exoribonuclease Activity Protein Binding
	Biological Process	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly	RRNA Processing RRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' U4 SnRNA 3'-end Processing Regulation Of MRNA Stability Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay DNA Deamination Defense Response To Virus Nuclear MRNA Surveillance Polyadenylation-dependent SnoRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 3' to 5' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Interacting Genes		26 interacting genes: ADAM15 ADAM9 AMPH APP ARHGAP17 BAX BIN1 CDKN2D CMTM5 COQ8A CSDE1 DNM2 EXOSC5 FUNDC1 GADD45A GADD45G HTATIP2 HTT MTA1 PSMA1 SH3GLB2 SH3KBP1 SYNJ1 TFIP11 TPD52L2 ZNF576	45 interacting genes: BIRC2 CALCOCO2 CDK5RAP1 DHRS2 DIS3 DMRTB1 DOCK8 EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FCHO1 FHL3 GOLGA2 HAMP HBS1L IKZF3 KIAA1217 KMT2A KRT13 LIPG LSM3 LSM5 MPHOSPH6 MPP6 MTREX NMI NUP210 PA2G4 PAF1 PKM POLR2L PRODH2 REL SFPQ SH3GLB1 SH3GLB2 TEX11 TNFAIP1 TRIM54 ZNF558
Entrez ID		51100	56915
HPRD ID		15333	16222
Ensembl ID		ENSG00000097033	ENSG00000077348
Uniprot IDs		A0A087WW40 A0A140VJU5 Q9Y371	Q9NQT4
PDB IDs			2NN6 6D6Q 6D6R 6H25
Enriched GO Terms of Interacting Partners?
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