PYCR2 and CIC

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

		PYCR2	CIC
Description		pyrroline-5-carboxylate reductase 2	capicua transcriptional repressor
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Pyrroline-5-carboxylate Reductase Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding
	Biological Process	Proline Biosynthetic Process Cellular Amino Acid Biosynthetic Process Cellular Response To Oxidative Stress Oxidation-reduction Process L-proline Biosynthetic Process	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development
Pathways		Glutamate and glutamine metabolism
Drugs		NADH L-Proline
Diseases
GWAS			Bitter alcoholic beverage consumption ( 31046077)
Interacting Genes		3 interacting genes: APP CIC SKIL	14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1
Entrez ID		29920	23152
HPRD ID		17939	10831
Ensembl ID		ENSG00000143811	ENSG00000079432
Uniprot IDs		A0A087WTV6 A0A0S2Z5U6 Q96C36	A0A0A0MQR4 Q96RK0
PDB IDs			2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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