CIC and TRIM22

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CIC	TRIM22
Description		capicua transcriptional repressor	tripartite motif containing 22
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Transferase Activity Protein Kinase Binding Protein Binding, Bridging Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development	Regulation Of Transcription, DNA-templated Immune Response Response To Virus Positive Regulation Of Autophagy Viral Process Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077)	Coronary artery disease ( 29212778)
Interacting Genes		14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1	10 interacting genes: CASK CIC CREB1 LGALS3 LGALS8 MFHAS1 RERE TAF7 USP7 ZZZ3
Entrez ID		23152	10346
HPRD ID		10831	05951
Ensembl ID		ENSG00000079432	ENSG00000132274
Uniprot IDs		A0A0A0MQR4 Q96RK0	B4DQS5 Q8IYM9
PDB IDs		2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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