GPSM2 and GLIS2

Number of citations of the paper that reports this interaction (PubMedID 17289029)
23

Data Source:
BioGRID (two hybrid)

		GPSM2	GLIS2
Description		G protein signaling modulator 2	GLIS family zinc finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Centrosome Cytosol Cell Cortex Lateral Plasma Membrane Protein-containing Complex Mitotic Spindle Pole Lateral Cell Cortex Cell Cortex Region	Nucleus Cytoplasm Nuclear Speck Non-motile Cilium
	Molecular Function	Nucleotide Binding G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Dynein Complex Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Spindle Organization G Protein-coupled Receptor Signaling Pathway Ran Protein Signal Transduction Regulation Of Catalytic Activity Cell Division Maintenance Of Centrosome Location Regulation Of Mitotic Spindle Organization Positive Regulation Of Protein Localization To Cell Cortex Positive Regulation Of Spindle Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription From RNA Polymerase II Promoter Involved In Kidney Development Cell Differentiation Involved In Kidney Development Positive Regulation Of Protein Localization To Nucleus
Pathways		G alpha (i) signalling events
Drugs
Diseases			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Fat distribution (HIV) ( 21897333)	Erectile dysfunction ( 30583798) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 26635082) Prostate-specific antigen levels ( 28139693)
Interacting Genes		10 interacting genes: AGR2 CLCC1 GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC NUMA1	49 interacting genes: AKT1 ARAF ARNT BCAR1 BECN1 CBLC CCND2 CCNE1 CD44 CDK4 CDK6 CDKN2A CDKN2B CPSF1 CTNNB1 EPHA2 ERBB2 FGFR4 FZR1 GLIS1 GPSM2 HGF HIF1A LATS2 MAP2K3 MAP2K5 MAP2K6 MAP3K5 MDM2 MDM4 MET MYC NF2 NFIC NSD3 PIK3CA RAF1 RASSF1 RBFOX2 SOX3 SPECC1L STK11 TEAD2 TERT TRIM32 U2AF2 WNK1 WT1 XAB2
Entrez ID		29899	84662
HPRD ID		06609	12256
Ensembl ID		ENSG00000121957	ENSG00000126603
Uniprot IDs		A0A024R0F8 B4DIF1 P81274	B3KTH4 Q9BZE0
PDB IDs		3SF4 4WND 4WNE 4WNF 4WNG 5A6C 6HC2
Enriched GO Terms of Interacting Partners?
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