GTF2H1 and RAD23A

Number of citations of the paper that reports this interaction (PubMedID 14706819)
9

Data Source:
BioGRID (pull down)

		GTF2H1	RAD23A
Description		general transcription factor IIH subunit 1	RAD23 homolog A, nucleotide excision repair protein
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GO Annotations	Cellular Component	Transcription Factor TFIIH Core Complex Nucleoplasm Transcription Factor TFIIH Holo Complex	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Protein Kinase Activity Protein Binding DNA-dependent ATPase Activity RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Nucleotide-excision Repair, DNA Duplex Unwinding DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Stabilization Nucleotide-excision Repair, Preincision Complex Assembly Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Nucleotide-excision Repair, DNA Incision Positive Regulation Of Transcription By RNA Polymerase II Phosphorylation Of RNA Polymerase II C-terminal Domain Global Genome Nucleotide-excision Repair	Nucleotide-excision Repair Viral Process Protein Deubiquitination Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Tat-mediated elongation of the HIV-1 transcript NoRC negatively regulates rRNA expression Formation of Incision Complex in GG-NER Dual Incision in GG-NER RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes mRNA Capping RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Transcription Termination RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE	Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Amyloid A serum levels ( 21124955) Blood protein levels ( 28240269) Pancreatic cancer ( 23180869) Serum metabolite levels ( 23093944) Survival in pancreatic cancer ( 28470677)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		44 interacting genes: ACTN1 AR ATF7IP BRPF1 CCNH CCSER2 CDK7 E2F1 ERCC2 ERCC3 ERCC4 ERCC5 ESR1 FUBP1 GTF2E1 GTF2E2 GTF2H2 GTF2H3 HNF4A HNRNPU HOXC11 JDP2 KIF13A KPNA3 MCM2 MMS19 MNAT1 PIK3R1 PLCG1 POLR2A POU2AF1 PSMC2 RAD23A REEP5 RXRB TNIP1 TP53 TRIOBP TXNRD2 UBC USHBP1 XPA XPC ZSCAN1	53 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CHEK1 CREBBP DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 HSPB1 IFIT3 IFIT5 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MPG NEDD8 NGLY1 PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RNF115 RNF32 RPN1 SMURF1 SQSTM1 TRAF2 TRAF5 TRIM54 TRIP6 UBB UBC UBE3A UBE4B UBL7 UBQLN4 USP25 VAV2 XPC ZBTB44 ZBTB8A
Entrez ID		2965	5886
HPRD ID		01807	07191
Ensembl ID		ENSG00000110768	ENSG00000179262
Uniprot IDs		A0A384MTQ8 P32780	A0A024R7G8 A8K1J3 P54725
PDB IDs		1PFJ 2DII 2RNR 2RUK 2RVB 5GOW 5XV8 6NMI 6O9L 6O9M	1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ 5XBO
Enriched GO Terms of Interacting Partners?
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