GRIN2A and DLGAP1

  • Number of citations of the paper that reports this interaction (PubMedID 9286858)
  • 23
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

GRIN2A

DLGAP1

Description glutamate ionotropic receptor NMDA type subunit 2A DLG associated protein 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Chronic kidney disease ( 26420894)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Copper levels ( 26025379)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Hepatitis B ( 22004137)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Lung function (FVC) ( 30804560)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Tenofovir clearance in HIV infection ( 26148204)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
  • Alanine aminotransferase levels ( 31219225)
  • Body fat mass ( 28552196)
  • Cardiac Troponin-T levels ( 23247143)
  • Eating disorders ( 22911880)
  • Economic and political preferences (time) ( 22566634)
  • Erythrocyte cadmium concentration in never smokers ( 27005419)
  • Hip circumference adjusted for BMI ( 28552196)
  • Initial alcohol sensitivity ( 30276832)
  • Menarche (age at onset) ( 27182965 25231870)
  • Midgestational circulating levels of PBDEs ( 28235828)
  • Obesity-related traits ( 23251661)
  • Plasma free amino acid levels ( 30659259)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
  • Trunk fat mass ( 28552196)
  • Upper eyelid sagging severity ( 24869959)
Interacting Genes 28 interacting genes: ACTN1 AKT1 AP1M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CASK CDK5 DLG1 DLG2 DLG3 DLG4 DLGAP1 FYN GRIN1 GRIN3A GRIN3B IL16 NEDD4 PATJ PLCG1 PRKCA PTK2B PTPN4 RGS3 SPTAN1 SRC 21 interacting genes: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1
Entrez ID 2903 9229
HPRD ID 00698 09260
Ensembl ID ENSG00000183454 ENSG00000170579
Uniprot IDs Q12879 Q547U9 Q59EW6 A0A0A0MTP4 A8MXQ8 B7Z2J5 O14490 Q6IS01
PDB IDs 3NFL 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH 5YPO
Enriched GO Terms of Interacting Partners?
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