GRIN2A and RGS3

  • Number of citations of the paper that reports this interaction (PubMedID 16637659)
  • 25
  • Data Source:
  • HPRD (in vitro)

GRIN2A

RGS3

Description glutamate ionotropic receptor NMDA type subunit 2A regulator of G protein signaling 3
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Chronic kidney disease ( 26420894)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Copper levels ( 26025379)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Hepatitis B ( 22004137)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Lung function (FVC) ( 30804560)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Tenofovir clearance in HIV infection ( 26148204)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 28 interacting genes: ACTN1 AKT1 AP1M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CASK CDK5 DLG1 DLG2 DLG3 DLG4 DLGAP1 FYN GRIN1 GRIN3A GRIN3B IL16 NEDD4 PATJ PLCG1 PRKCA PTK2B PTPN4 RGS3 SPTAN1 SRC 23 interacting genes: ACD APP CNKSR2 DEPDC1B EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PAX6 PLSCR1 PRKN SCN5A YWHAB YWHAE YWHAQ YWHAZ
Entrez ID 2903 5998
HPRD ID 00698 03720
Ensembl ID ENSG00000183454 ENSG00000138835
Uniprot IDs Q12879 Q547U9 Q59EW6 A0A024R831 A0A024R833 A0A024R841 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3
PDB IDs 3NFL 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH 2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?
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