GRIN2A and PTK2B

  • Number of citations of the paper that reports this interaction (PubMedID 11478920)
  • 16
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

GRIN2A

PTK2B

Description glutamate ionotropic receptor NMDA type subunit 2A protein tyrosine kinase 2 beta
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Chronic kidney disease ( 26420894)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Copper levels ( 26025379)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Hepatitis B ( 22004137)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Lung function (FVC) ( 30804560)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Tenofovir clearance in HIV infection ( 26148204)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 28 interacting genes: ACTN1 AKT1 AP1M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CASK CDK5 DLG1 DLG2 DLG3 DLG4 DLGAP1 FYN GRIN1 GRIN3A GRIN3B IL16 NEDD4 PATJ PLCG1 PRKCA PTK2B PTPN4 RGS3 SPTAN1 SRC 69 interacting genes: ARHGAP21 ARHGAP5 ASAP1 ASAP2 BCAR1 CBL CCR5 CRK DLG3 DLG4 DLGAP3 EFS EGFR ERBB2 ERBB3 EWSR1 FGFR2 FGFR3 FLT1 FYN GNA13 GRB2 GRIN2A GSN IL7R ITGB2 ITGB3 JAK1 JAK2 JAK3 KCNA2 LCK LPXN LYN MAP3K4 MAPT MATK MCAM MYH2 NEDD9 NPHP1 PDCD6IP PDPK1 PIK3R1 PITPNM1 PITPNM2 PITPNM3 PRKCD PTK2 PTPN11 PTPN12 PTPN6 PXN RASA1 RB1CC1 SH2D3C SHC1 SKAP2 SLC2A1 SNCA SORBS2 SRC STAP1 STAT3 SYK TGFB1I1 TLN1 VAV1 ZAP70
Entrez ID 2903 2185
HPRD ID 00698 03131
Ensembl ID ENSG00000183454 ENSG00000120899
Uniprot IDs Q12879 Q547U9 Q59EW6 Q14289
PDB IDs 3NFL 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH 2FO6 2LK4 3CC6 3ET7 3FZO 3FZP 3FZR 3FZS 3FZT 3GM1 3GM2 3GM3 3H3C 3U3F 4EKU 4H1J 4H1M 4R32 4XEF 4XEK 4XEV 5TO8 5TOB
Enriched GO Terms of Interacting Partners?
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