RND1 and FRS3

Number of citations of the paper that reports this interaction (PubMedID 15738000)
14

Data Source:
HPRD (in vitro)

		RND1	FRS3
Description		Rho family GTPase 1	fibroblast growth factor receptor substrate 3
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle	Plasma Membrane
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding	Fibroblast Growth Factor Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Cytokinesis Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Neuron Remodeling Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly	MAPK Cascade Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse	FRS-mediated FGFR1 signaling FRS-mediated FGFR2 signaling FRS-mediated FGFR3 signaling FRS-mediated FGFR4 signaling RAF/MAP kinase cascade Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Menarche (age at onset) ( 25231870)
Interacting Genes		12 interacting genes: ARHGAP5 CREB3L2 FRS2 FRS3 GRB7 ID3 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212	28 interacting genes: ADAMTSL4 BMPR2 CBY2 DDX5 FGFR1 GATA1 GRB14 GRB2 KARS1 MAPK1 MATK NOTCH2NLA NTRK1 NTRK2 NUMB PLSCR1 PRKCI PTPN11 RFX6 RND1 SH2B1 SOCS6 SPRY2 TCF4 TLE5 TNS1 TRIP6 VASP
Entrez ID		27289	10817
HPRD ID		12357	06373
Ensembl ID		ENSG00000172602	ENSG00000137218
Uniprot IDs		Q92730	A0A140VJJ7 O43559
PDB IDs		2CLS 2REX 3Q3J	2KUP 2KUQ 2YS5 2YT2
Enriched GO Terms of Interacting Partners?
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