SIT1 and ZAP70

  • Number of citations of the paper that reports this interaction (PubMedID 10209036)
  • 14
  • Data Source:
  • HPRD (in vivo)

SIT1

ZAP70

Description signaling threshold regulating transmembrane adaptor 1 zeta chain of T cell receptor associated protein kinase 70
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Interacting Genes 7 interacting genes: CSK FYN GRB2 LCK PTPN11 SYK ZAP70 62 interacting genes: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK DAPK1 DBNL DEF6 DUSP3 EGFR ERBB3 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 LAT LAX1 LCK LCP2 LRRK2 MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 RNF41 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP USP2 VAV1 WIPF1
Entrez ID 27240 7535
HPRD ID 05394 01495
Ensembl ID ENSG00000137078 ENSG00000115085
Uniprot IDs Q9Y3P8 P43403
PDB IDs 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R 4XZ0 4XZ1 5O76
Enriched GO Terms of Interacting Partners?
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