HSPB7 and SF3B4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HSPB7	SF3B4
Description		heat shock protein family B (small) member 7	splicing factor 3b subunit 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cajal Body Aggresome	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Ribonucleoprotein Complex
	Molecular Function	Protein Binding Protein C-terminus Binding	RNA Binding Protein Binding Splicing Factor Binding
	Biological Process	Response To Unfolded Protein Heart Development Regulation Of Heart Contraction	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Arterial stiffness index ( 31235810) Erectile dysfunction ( 30583798) Systolic blood pressure ( 28739976)	Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth length ( 25281659) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 20881960 31562340 18391951) Infant length ( 25281659) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		10 interacting genes: APP CEP76 HSPB8 PLEKHF2 PRDM14 REL SF3B4 SYCE1 TCF4 TRIM23	42 interacting genes: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM10 RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A WBP4 WDR77 ZCCHC10
Entrez ID		27129	10262
HPRD ID		13684	12028
Ensembl ID		ENSG00000173641	ENSG00000143368
Uniprot IDs		Q9UBY9	B3KUJ0 Q15427
PDB IDs			1X5T 5GVQ 5Z56 5Z57 5Z58 6AH0 6QX9
Enriched GO Terms of Interacting Partners?
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