SF3B4 and EFTUD2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology)

		SF3B4	EFTUD2
Description		splicing factor 3b subunit 4	elongation factor Tu GTP binding domain containing 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytosol Cajal Body Membrane Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Splicing Factor Binding	RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process	MRNA Splicing, Via Spliceosome Cellular Response To Drug Response To Cocaine
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth length ( 25281659) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 20881960 31562340 18391951) Infant length ( 25281659) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412)	Asthma ( 31619474) Craniofacial microsomia ( 26853712)
Interacting Genes		42 interacting genes: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM10 RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A WBP4 WDR77 ZCCHC10	12 interacting genes: ARPC3 CYFIP1 GOLM1 GSK3B HINFP LSM8 PIN1 SF3B3 SF3B4 SNRNP200 SREK1 WBP4
Entrez ID		10262	9343
HPRD ID		12028	04869
Ensembl ID		ENSG00000143368	ENSG00000108883
Uniprot IDs		B3KUJ0 Q15427	B3KX19 Q15029
PDB IDs		1X5T 5GVQ 5Z56 5Z57 5Z58 6AH0 6QX9	3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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