RNF11 and STAM2

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		RNF11	STAM2
Description		ring finger protein 11	signal transducing adaptor molecule 2
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination	Intracellular Protein Transport Endosomal Transport Macroautophagy Protein Deubiquitination Multivesicular Body Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways			EGFR downregulation Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)	Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Metabolic syndrome ( 31170924) Pulse pressure ( 30224653)
Interacting Genes		66 interacting genes: AKT1 ANKRD13A APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350	35 interacting genes: ABI2 ARRDC3 ATXN1 CBX5 DAZAP2 EGFR EPS15 FAM189A2 HGS ITCH JAK1 JAK2 JAK3 KLHL42 L3MBTL2 LCP2 LITAF MAP3K1 PHF10 PLEKHB2 PTPN1 RNF11 SH2D4A STAMBP TIMM8A TYK2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBQLN4 USP8 VPS37C XRN1
Entrez ID		26994	10254
HPRD ID		09955	05876
Ensembl ID		ENSG00000123091	ENSG00000115145
Uniprot IDs		Q9Y3C5	O75886
PDB IDs			1X2Q 1X5B 2L0T 5CRV 5IXF
Enriched GO Terms of Interacting Partners?
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