SH3YL1 and VPS37B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		SH3YL1	VPS37B
Description		SH3 and SYLF domain containing 1	VPS37B subunit of ESCRT-I
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Membrane	ESCRT I Complex Cytoplasm Endosome Plasma Membrane Endosome Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome
	Molecular Function	Protein Binding Phosphatase Binding Phosphatidylinositol Binding	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Ruffle Assembly	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Budding Via Host ESCRT Complex
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Blood urea nitrogen levels ( 31152163) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Estimated glomerular filtration rate ( 31152163) HDL cholesterol ( 30275531) Large artery stroke ( 28265093) Mitochondrial DNA levels ( 25240745) Night sleep phenotypes ( 27126917)	Tourette syndrome ( 30818990)
Interacting Genes		9 interacting genes: AR ERRFI1 GFAP HELZ KHDRBS1 SH3D19 VIM VPS37B ZBTB7B	16 interacting genes: BYSL CDC73 DCUN1D1 ERCC1 FBF1 HGS NCK2 PRKAA1 QARS1 SH3YL1 SMARCD1 SORBS3 TLE5 TSG101 UBASH3B VPS28
Entrez ID		26751	79720
HPRD ID		15336	07794
Ensembl ID		ENSG00000035115	ENSG00000139722
Uniprot IDs		Q96HL8	A0A024RBU0 Q9H9H4
PDB IDs		2D8H
Enriched GO Terms of Interacting Partners?
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