SH3YL1 and GFAP

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SH3YL1	GFAP
Description		SH3 and SYLF domain containing 1	glial fibrillary acidic protein
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GO Annotations	Cellular Component	Ruffle Membrane	Cytoplasm Lysosome Cytosol Intermediate Filament Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Phosphatase Binding Phosphatidylinositol Binding	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Regulation Of Ruffle Assembly	Regulation Of Protein Complex Assembly Intermediate Filament Organization Regulation Of Chaperone-mediated Autophagy
Pathways			Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases			Alexander disease
GWAS		Blood protein levels ( 28240269) Blood urea nitrogen levels ( 31152163) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Estimated glomerular filtration rate ( 31152163) HDL cholesterol ( 30275531) Large artery stroke ( 28265093) Mitochondrial DNA levels ( 25240745) Night sleep phenotypes ( 27126917)	Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)
Interacting Genes		9 interacting genes: AR ERRFI1 GFAP HELZ KHDRBS1 SH3D19 VIM VPS37B ZBTB7B	51 interacting genes: AKT1 APP AURKB BIRC2 CAMK2A CDK1 CEP76 CFAP206 CRYAB FAM50B GOLGA2 GRAP2 HGS IKBKG KIAA0408 KRT13 KRT15 KRT19 LGALS14 LMO2 MEN1 MOS MYO15B NEFL NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCB1 SRC STAT1 TLE5 TRIM27 TUBGCP4 UBE3A VIM ZC2HC1C
Entrez ID		26751	2670
HPRD ID		15336	00675
Ensembl ID		ENSG00000035115	ENSG00000131095
Uniprot IDs		Q96HL8	A7REI1 P14136
PDB IDs		2D8H	6A9P
Enriched GO Terms of Interacting Partners?
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