LATS2 and KIF23

Number of citations of the paper that reports this interaction (PubMedID 25658096)
3

Data Source:
BioGRID (enzymatic study)

		LATS2	KIF23
Description		large tumor suppressor kinase 2	kinesin family member 23
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GO Annotations	Cellular Component	Spindle Pole Nucleus Cytosol Centriolar Satellite	Cell Nucleus Nucleoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion Midbody Intercellular Bridge Mitotic Spindle Flemming Body Centralspindlin Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Hormone-mediated Signaling Pathway Peptidyl-serine Phosphorylation Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway	Mitotic Spindle Elongation Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Plus-end-directed Vesicle Transport Along Microtubule
Pathways		Signaling by Hippo	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)	Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		71 interacting genes: ABL1 AJUBA AKT1 AMOT ARAF ARNT AURKA AURKB BECN1 BRAF CBLC CCND2 CCNE1 CD44 CDK2 CDK4 CDK6 CDKN1A CDKN2A CDKN2B CDKN2C CHEK1 CHEK2 CTNNB1 DYRK1A EPHA2 ERBB2 EZH2 FGFR4 FHL3 FZR1 GLIS1 GLIS2 GRAP2 GRM1 HGF HIF1A KAT2A KDELR2 KIF23 MAP2K3 MAP2K5 MAP3K5 MAPK14 MDM4 MET MOB3A MOB3B MOB3C MOB4 MYC NF2 NFIC PDGFRA RAF1 RASSF1 RELA SMAD2 SNAI1 STK11 STK3 STK4 SUZ12 TAZ TEAD2 TP53 TSC1 WWTR1 YAP1 YWHAG YWHAZ	11 interacting genes: ACTA1 ARF3 CLK1 LATS2 PLK1 RACGAP1 RBM34 USP8 YWHAB YWHAG YWHAQ
Entrez ID		26524	9493
HPRD ID		07277	05455
Ensembl ID		ENSG00000150457	ENSG00000137807
Uniprot IDs		A0A024RDM3 Q9NRM7	Q02241
PDB IDs		4ZRI	3VHX
Enriched GO Terms of Interacting Partners?
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