LATS2 and GLIS1

Number of citations of the paper that reports this interaction (PubMedID 28205554)
32

Data Source:
BioGRID (fluorescent resonance energy transfer)

		LATS2	GLIS1
Description		large tumor suppressor kinase 2	GLIS family zinc finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytosol Centriolar Satellite	Nucleus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Hormone-mediated Signaling Pathway Peptidyl-serine Phosphorylation Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Negative Regulation Of Cell Fate Commitment Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)	Cerebrospinal fluid AB1-42 levels ( 28247064) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Hand grip strength ( 29691431 29313844) Mitral valve prolapse ( 26301497) Monobrow ( 27182965) Nicotine use ( 23942779) Non-substance related behavioral disinhibition ( 23942779) Nose size ( 27182965) Response to statin therapy ( 20339536)
Interacting Genes		71 interacting genes: ABL1 AJUBA AKT1 AMOT ARAF ARNT AURKA AURKB BECN1 BRAF CBLC CCND2 CCNE1 CD44 CDK2 CDK4 CDK6 CDKN1A CDKN2A CDKN2B CDKN2C CHEK1 CHEK2 CTNNB1 DYRK1A EPHA2 ERBB2 EZH2 FGFR4 FHL3 FZR1 GLIS1 GLIS2 GRAP2 GRM1 HGF HIF1A KAT2A KDELR2 KIF23 MAP2K3 MAP2K5 MAP3K5 MAPK14 MDM4 MET MOB3A MOB3B MOB3C MOB4 MYC NF2 NFIC PDGFRA RAF1 RASSF1 RELA SMAD2 SNAI1 STK11 STK3 STK4 SUZ12 TAZ TEAD2 TP53 TSC1 WWTR1 YAP1 YWHAG YWHAZ	11 interacting genes: ARNT CDK6 CDKN2A GLIS2 LATS2 MYC NFIC RELA SOX3 TCF3 TEAD2
Entrez ID		26524	148979
HPRD ID		07277	13581
Ensembl ID		ENSG00000150457	ENSG00000174332
Uniprot IDs		A0A024RDM3 Q9NRM7	A0A0D9SEX9 Q8NBF1
PDB IDs		4ZRI
Enriched GO Terms of Interacting Partners?
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