BLOC1S1 and PBX2

Number of citations of the paper that reports this interaction (PubMedID 14667819)
35

Data Source:
HPRD (two hybrid)

		BLOC1S1	PBX2
Description		biogenesis of lysosomal organelles complex 1 subunit 1	PBX homeobox 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex BORC Complex Axon Cytoplasm	Nuclear Chromatin Nucleus Transcription Factor Complex
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding
	Biological Process	Anterograde Axonal Transport Aerobic Respiration Endosomal Transport Peptidyl-lysine Acetylation Neuron Projection Development Lysosome Localization Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization	Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Crohn's disease ( 23266558) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908)
Interacting Genes		12 interacting genes: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 MTA1 NOTCH1 PBX2 PELP1 PTN SNAPIN	22 interacting genes: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 ELP1 HOXA1 HOXA9 HOXB8 MCRS1 MTREX NEU1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SMYD3 UBE2E1 ZDHHC7
Entrez ID		2647	5089
HPRD ID		03263	08890
Ensembl ID		ENSG00000135441	ENSG00000204304
Uniprot IDs		P78537	A0A024RCR3 P40425
PDB IDs
Enriched GO Terms of Interacting Partners?
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