GARS1 and IARS1

Number of citations of the paper that reports this interaction (PubMedID 8816763)
24

Data Source:
HPRD (two hybrid)

		GARS1	IARS1
Description		glycyl-tRNA synthetase 1	isoleucyl-tRNA synthetase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Secretory Granule Axon Extracellular Exosome	Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome
	Molecular Function	Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) Activity Glycine-tRNA Ligase Activity Protein Binding ATP Binding Transferase Activity Identical Protein Binding Protein Dimerization Activity	TRNA Binding Aminoacyl-tRNA Editing Activity Isoleucine-tRNA Ligase Activity Protein Binding ATP Binding GTPase Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Glycyl-tRNA Aminoacylation Diadenosine Tetraphosphate Biosynthetic Process Mitochondrial Glycyl-tRNA Aminoacylation	Osteoblast Differentiation TRNA Aminoacylation For Protein Translation Isoleucyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways		Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs		Glycine	L-Isoleucine
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS
Interacting Genes		9 interacting genes: CD44 CELSR2 EEF1D HSPB2 IARS1 MAP3K10 MAPK8 NAE1 NEDD8	6 interacting genes: APP AR EPRS1 ERBB2 GARS1 SNCA
Entrez ID		2617	3376
HPRD ID		02617	02832
Ensembl ID		ENSG00000106105	ENSG00000196305
Uniprot IDs		A0A090N8G0 P41250	P41252 Q6P0M4 Q7L4K8
PDB IDs		2PME 2PMF 2Q5H 2Q5I 2ZT5 2ZT6 2ZT7 2ZT8 2ZXF 4KQE 4KR2 4KR3 4QEI 5E6M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?