GARS1

Description		glycyl-tRNA synthetase 1
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Secretory Granule Axon Extracellular Exosome
	Molecular Function	Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) Activity Glycine-tRNA Ligase Activity Protein Binding ATP Binding Transferase Activity Identical Protein Binding Protein Dimerization Activity
	Biological Process	TRNA Aminoacylation For Protein Translation Glycyl-tRNA Aminoacylation Diadenosine Tetraphosphate Biosynthetic Process Mitochondrial Glycyl-tRNA Aminoacylation
Pathways		Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation
Drugs		Glycine
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS
Interacting Genes		9 interacting genes: CD44 CELSR2 EEF1D HSPB2 IARS1 MAP3K10 MAPK8 NAE1 NEDD8
Entrez ID		2617
HPRD ID		02617
Ensembl ID		ENSG00000106105
Uniprot IDs		A0A090N8G0 P41250
PDB IDs		2PME 2PMF 2Q5H 2Q5I 2ZT5 2ZT6 2ZT7 2ZT8 2ZXF 4KQE 4KR2 4KR3 4QEI 5E6M
Enriched GO Terms of Interacting Partners?
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