GGA1 and SCARB1

GGA1

SCARB1

Description golgi associated, gamma adaptin ear containing, ARF binding protein 1 scavenger receptor class B member 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Coronary artery disease ( 29212778)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • HDL cholesterol ( 24097068 30275531 25961943 20686565)
  • HDL cholesterol levels ( 28334899 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 31217584)
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
  • Lipoprotein-associated phospholipase A2 activity and mass ( 23118302 20442857)
  • Lung function (FEV1) ( 30061609)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels (lipoprotein measures) ( 27005778)
  • Renal cell carcinoma ( 21131975)
  • Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
  • Total bilirubin levels ( 29403010)
  • Total cholesterol levels ( 29403010)
  • Triglycerides ( 30275531)
  • Vitamin E levels ( 21729881)
Interacting Genes 38 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB EGFR F8 GGA2 GGA3 IGF2R LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SCARB1 SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18 16 interacting genes: APOA1 APOA2 APOE CASP10 DENR GGA1 GTF2H3 KRTAP10-9 KRTAP5-9 PDZK1 PEX5 POLE PRL PXN SNAP23 SRSF9
Entrez ID 26088 949
HPRD ID 12078 03024
Ensembl ID ENSG00000100083 ENSG00000073060
Uniprot IDs Q9UJY5 A0A024RBS4 Q8WTV0
PDB IDs 1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?
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