GGA1 and CDKL3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		GGA1	CDKL3
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 1	cyclin dependent kinase like 3
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GO Annotations	Cellular Component	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding ADP-ribosylation Factor Binding	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Health literacy ( 31250787)	Eosinophil counts ( 27863252) Moderate-to-late spontaneous preterm birth ( 31194736)
Interacting Genes		38 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB EGFR F8 GGA2 GGA3 IGF2R LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SCARB1 SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18	18 interacting genes: APP ATG4A DNAAF6 FXR2 GGA1 GOLGA2 KASH5 KRTAP10-9 LRRK2 LZTS2 MDFI MTUS2 SNRNP70 SRPK1 TRIM27 TTF2 ZBTB14 ZBTB8A
Entrez ID		26088	51265
HPRD ID		12078	09766
Ensembl ID		ENSG00000100083	ENSG00000006837
Uniprot IDs		Q9UJY5	B4DX41 Q8IVW4
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W	3ZDU
Enriched GO Terms of Interacting Partners?
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