ERC2 and PPFIA3

Number of citations of the paper that reports this interaction (PubMedID 12923177)
60

Data Source:
HPRD (in vitro, two hybrid)

		ERC2	PPFIA3
Description		ELKS/RAB6-interacting/CAST family member 2	PTPRF interacting protein alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Cell Junction Growth Cone Presynaptic Membrane Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse	Acrosomal Vesicle Cytosol Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse
	Molecular Function	Protein Binding Structural Constituent Of Presynaptic Active Zone	Protein Binding
	Biological Process	Synaptic Vesicle Priming Maintenance Of Presynaptic Active Zone Structure	Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization
Pathways			Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Alcohol dependence ( 24166409) Bipolar disorder and schizophrenia ( 21057379) Chronotype ( 26955885) Daytime sleep phenotypes ( 27126917) Heel bone mineral density ( 30598549 28869591) Hip bone size ( 31053729) Hip geometry ( 17903296) Intertrochanteric region size ( 31053729) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Morning vs. evening chronotype ( 26955885 27494321) Night sleep phenotypes ( 27126917) Periodontitis (Mean PAL) ( 24024966) Post bronchodilator FEV1/FVC ratio ( 26634245) Sense of smell ( 26632684) Tourette syndrome ( 30818990) Trochanter size ( 31053729)
Interacting Genes		8 interacting genes: BSN MYB PCLO PPFIA1 PPFIA2 PPFIA3 PPFIA4 RIMS1	11 interacting genes: CAST ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS PTPRU
Entrez ID		26059	8541
HPRD ID		10810	04393
Ensembl ID		ENSG00000187672	ENSG00000177380
Uniprot IDs		O15083	O75145
PDB IDs
Enriched GO Terms of Interacting Partners?
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