GABBR1 and ATF5

Number of citations of the paper that reports this interaction (PubMedID 11087824)
41

Data Source:
HPRD (two hybrid)

		GABBR1	ATF5
Description		gamma-aminobutyric acid type B receptor subunit 1	activating transcription factor 5
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite G Protein-coupled Receptor Heterodimeric Complex Presynaptic Membrane Postsynaptic Membrane Schaffer Collateral - CA1 Synapse GABA-ergic Synapse	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Centrosome Cytosol
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled GABA Receptor Activity Protein Binding G Protein-coupled Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Tubulin Binding Kinase Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Gamma-aminobutyric Acid Signaling Pathway Regulation Of Postsynaptic Membrane Potential	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Negative Regulation Of Cell Proliferation Post-embryonic Development Olfactory Bulb Interneuron Development Cerebellar Granule Cell Precursor Proliferation Multicellular Organism Growth Negative Regulation Of Apoptotic Process Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centrosome Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition
Pathways		Activation of G protein gated Potassium channels G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) GABA B receptor activation Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Response of EIF2AK1 (HRI) to heme deficiency
Drugs		Baclofen Progabide Gabapentin Vigabatrin Taurine gamma-Aminobutyric acid SGS-742 Arbaclofen Arbaclofen Placarbil	Pseudoephedrine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 22412388) Height ( 28552196) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Nasopharyngeal carcinoma ( 19664746) Nicotine dependence ( 28440896) Platelet count ( 26805783) Schizophrenia ( 27922604) Ulna and radius bone mineral density ( 30172743) White blood cell count ( 27863252)
Interacting Genes		11 interacting genes: ATF5 CHFR CPEB2 GABBR2 GNAO1 JAKMIP1 KCNJ6 MAX NSF RGS4 YWHAZ	12 interacting genes: ATXN1 CCND3 CDC34 CEBPA CEBPE CEBPG DISC1 EP300 FBXO7 GABBR1 GABBR2 GIT2
Entrez ID		2550	22809
HPRD ID		04644	05906
Ensembl ID		ENSG00000204681	ENSG00000169136
Uniprot IDs		A0A1U9X7R0 Q59HG8 Q5SUJ9 Q8IW08 Q9UBS5	A0A024QZG3 Q9Y2D1
PDB IDs		4MQE 4MQF 4MR7 4MR8 4MR9 4MRM 4MS1 4MS3 4MS4 4PAS 6HKC
Enriched GO Terms of Interacting Partners?
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