ATF5 and GABBR2

Number of citations of the paper that reports this interaction (PubMedID 11087824)
41

Data Source:
HPRD (two hybrid)

		ATF5	GABBR2
Description		activating transcription factor 5	gamma-aminobutyric acid type B receptor subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Centrosome Cytosol	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction G Protein-coupled Receptor Heterodimeric Complex Neuron Projection Postsynaptic Membrane GABA Receptor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Tubulin Binding Kinase Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	Transmembrane Signaling Receptor Activity G Protein-coupled GABA Receptor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Rhythm Negative Regulation Of Cell Proliferation Post-embryonic Development Olfactory Bulb Interneuron Development Cerebellar Granule Cell Precursor Proliferation Multicellular Organism Growth Negative Regulation Of Apoptotic Process Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Centrosome Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission
Pathways		Response of EIF2AK1 (HRI) to heme deficiency	Activation of G protein gated Potassium channels G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) GABA B receptor activation Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Pseudoephedrine	Baclofen Gabapentin gamma-Aminobutyric acid SGS-742 Arbaclofen Arbaclofen Placarbil
Diseases
GWAS			High chromosomal aberration frequency (chromatid type) ( 31586183) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Response to simvastatin treatment (PCSK9 protein level change) ( 25089948) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Schizophrenia ( 30285260) Systolic blood pressure change trajectories ( 27980656)
Interacting Genes		12 interacting genes: ATXN1 CCND3 CDC34 CEBPA CEBPE CEBPG DISC1 EP300 FBXO7 GABBR1 GABBR2 GIT2	9 interacting genes: ATF4 ATF5 GABBR1 GLP1R HTR1A KCTD12 NSF SH3GL3 TAMALIN
Entrez ID		22809	9568
HPRD ID		05906	09552
Ensembl ID		ENSG00000169136	ENSG00000136928
Uniprot IDs		A0A024QZG3 Q9Y2D1	H9NIL8 O75899
PDB IDs			4F11 4F12 4MQE 4MQF 4MR7 4MR8 4MR9 4MRM 4MS1 4MS3 4MS4 4PAS 6M8R 6OCP
Enriched GO Terms of Interacting Partners?
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