ZBTB38 and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZBTB38	RALBP1
Description		zinc finger and BTB domain containing 38	ralA binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Blood Microparticle	Cytosol Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Methyl-CpG Binding Protein Homodimerization Activity Metal Ion Binding	GTPase Activator Activity Protein Binding Ral GTPase Binding Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Rac GTPase Binding
	Biological Process	Regulation Of DNA Replication Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Drug Transmembrane Export
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS		Advanced glycation end-product levels ( 26915486) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Blond vs. brown/black hair color ( 30531825) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Breast cancer ( 29059683) Brown vs. black hair color ( 30531825) Chronic obstructive pulmonary disease ( 30804561) Crohn's disease ( 28067908) Diastolic blood pressure ( 27618447) Estimated glomerular filtration rate ( 31152163) Hair color ( 29662168) Heel bone mineral density ( 30598549) Height ( 21998595 28552196 20881960 25282103 25429064 19396169 19343178 19893584 23563607 31562340 28270201 18391950 18391951 18391952 18193045 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412) Infant length ( 25281659) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602) Myopia ( 27182965) Non-albumin protein levels ( 29403010) Offspring birth weight ( 31043758) Prion diseases ( 22210626) Prostate cancer ( 21743467) Prostate-specific antigen levels (conditioned on lead SNPs) ( 28139693) Pulmonary function in asthmatics ( 25221879) Red blood cell count ( 27863252) Serum total protein level ( 29403010) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27618447) Waist circumference ( 25673412) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in inactive individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 25673412 28448500) Weight ( 28552196)	LDL cholesterol ( 30275531)
Interacting Genes		14 interacting genes: CBFA2T3 CCDC136 EHMT2 FSD2 KRT40 KRTAP10-7 KRTAP10-9 LZTS2 MTUS2 PDE4DIP RALBP1 RBBP6 TRIM41 TSGA10	30 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GSE1 HOOK2 HSF1 IKBKG PLCG2 PPL PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		253461	10928
HPRD ID		10985	09013
Ensembl ID		ENSG00000177311	ENSG00000017797
Uniprot IDs		Q8NAP3 Q9H6F0	Q15311
PDB IDs		6E93 6E94	2KWH 2KWI 2MBG
Enriched GO Terms of Interacting Partners?
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