FYB1 and CBLB

Number of citations of the paper that reports this interaction (PubMedID 16503409)
10

Data Source:
HPRD (in vivo)

		FYB1	CBLB
Description		FYN binding protein 1	Cbl proto-oncogene B
Image
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Protein-containing Complex	Nucleoplasm Cytosol Plasma Membrane Membrane Raft
	Molecular Function	Signaling Receptor Binding Protein Binding Lipid Binding Protein-containing Complex Binding	Phosphotyrosine Residue Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Receptor Tyrosine Kinase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Immune Response Integrin-mediated Signaling Pathway Biological_process T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane	NLS-bearing Protein Import Into Nucleus Signal Transduction Cell Surface Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway
Pathways		Generation of second messenger molecules Generation of second messenger molecules Signal regulatory protein family interactions	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Antipsychotic drug-induced weight gain in schizophrenia or autism ( 31447353) Estimated glomerular filtration rate ( 31152163) Itch intensity from mosquito bite ( 28199695) Mosquito bite size ( 28199695) Multiple sclerosis ( 31604244 20453840 28445677) Waist circumference ( 31647587) Zinc levels ( 26025379)
Interacting Genes		15 interacting genes: BCAR1 CBL CBLB ENAH EVL FASLG FYN LCP2 NCK2 SH2D1A SKAP1 SKAP2 SRC VASP WAS	46 interacting genes: APPL1 ARHGEF7 BLNK CD2AP CRK CRKL CRY1 DAPK1 DUXAP9 EGFR FLT3 FYB1 FYN GLRX3 GORASP2 GRAP2 GRB2 HNRNPK KIT LRRK1 LRRK2 MFHAS1 NCK1 NCK2 NEDD4 NEDD8 PIK3R1 PLCG2 PRMT2 RET RNF11 SH3KBP1 SHC1 SORBS3 SP7 SPRY2 SYK TGFB1I1 TNFRSF11A UBASH3B UBC UBE2D2 UBE2L3 VAV1 VAV2 ZAP70
Entrez ID		2533	868
HPRD ID		04107	05136
Ensembl ID		ENSG00000082074	ENSG00000114423
Uniprot IDs		O15117	B3KSS7 B4DYP3 B7ZAG1 H0Y3L9 Q13191
PDB IDs		1RI9 2GTJ 2GTO	2AK5 2BZ8 2DO6 2J6F 2JNH 2LDR 2OOA 2OOB 3PFV 3VGO 3ZNI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?