FUT1 and VPS11

		FUT1	VPS11
Description		fucosyltransferase 1 (H blood group)	VPS11 core subunit of CORVET and HOPS complexes
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Integral Component Of Plasma Membrane Membrane Golgi Cisterna Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane
	Molecular Function	Galactoside 2-alpha-L-fucosyltransferase Activity Fucosyltransferase Activity	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Fucosylation L-fucose Catabolic Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Regulation Of Protein Stability Endosomal Vesicle Fusion Regulation Of SNARE Complex Assembly Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		ABO blood group biosynthesis
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Bipolar disorder ( 21926972) Dietary macronutrient intake ( 23372041) Elevated serum carcinoembryonic antigen levels ( 24941225) Intake of total sugars ( 31005972) Retinal vascular caliber ( 21060863) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Body mass index ( 29273807) Coronary artery disease ( 29212778)
Interacting Genes		1 interacting genes: VPS11	37 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS45 WNT1
Entrez ID		2523	55823
HPRD ID		07186	12258
Ensembl ID		ENSG00000174951	ENSG00000160695
Uniprot IDs		P19526 Q6IZA2	A0A087WXL6 B7Z879 Q9H270
PDB IDs
Enriched GO Terms of Interacting Partners?
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