KIF4A and PRC1

Number of citations of the paper that reports this interaction (PubMedID 15297875)
117

Data Source:
BioGRID (affinity chromatography technology, pull down, two hybrid)

		KIF4A	PRC1
Description		kinesin family member 4A	protein regulator of cytokinesis 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Cytoplasm Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Matrix Midbody Axon Cytoplasm	Spindle Pole Nucleus Nucleoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring
	Molecular Function	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding
	Biological Process	Mitotic Cytokinesis Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Anterograde Axonal Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Mitotic Spindle Midzone Assembly	Mitotic Spindle Elongation Microtubule Bundle Formation Positive Regulation Of Cell Proliferation Regulation Of Cytokinesis Cell Division
Pathways		MHC class II antigen presentation Recycling pathway of L1 Recycling pathway of L1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	RHO GTPases activate CIT
Drugs
Diseases
GWAS			Breast cancer ( 29059683 25038754) Mean platelet volume ( 27863252) Multisite chronic pain ( 31194737) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 20581827 30718926 28869590)
Interacting Genes		6 interacting genes: APP DNMT3B HMG20B PDZD11 PRC1 TTF2	25 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 NDEL1 PCM1 PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 TRIM37 USHBP1 YWHAE
Entrez ID		24137	9055
HPRD ID		06606	17899
Ensembl ID		ENSG00000090889	ENSG00000198901
Uniprot IDs		O95239 Q59HG1	A0A024RC67 O43663
PDB IDs			3NRX 3NRY 4L3I 4L6Y 5KMG
Enriched GO Terms of Interacting Partners?
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