PRC1 and KLC2

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		PRC1	KLC2
Description		protein regulator of cytokinesis 1	kinesin light chain 2
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding	Microtubule Motor Activity Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Mitotic Spindle Elongation Microtubule Bundle Formation Positive Regulation Of Cell Proliferation Regulation Of Cytokinesis Cell Division	Retrograde Vesicle-mediated Transport, Golgi To ER Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		RHO GTPases activate CIT	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Breast cancer ( 29059683 25038754) Mean platelet volume ( 27863252) Multisite chronic pain ( 31194737) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 20581827 30718926 28869590)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		25 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 NDEL1 PCM1 PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 TRIM37 USHBP1 YWHAE	16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		9055	64837
HPRD ID		17899	13917
Ensembl ID		ENSG00000198901	ENSG00000174996
Uniprot IDs		A0A024RC67 O43663	Q9H0B6
PDB IDs		3NRX 3NRY 4L3I 4L6Y 5KMG	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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