PLA2G15 and RNF7

Number of citations of the paper that reports this interaction (PubMedID 10230407)
159

Data Source:
HPRD (in vivo, two hybrid)

		PLA2G15	RNF7
Description		phospholipase A2 group XV	ring finger protein 7
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Nuclear SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Lysophospholipase Activity Phospholipid Binding O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding
	Biological Process	Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein Neddylation Response To Redox State
Pathways		Hydrolysis of LPC	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Schizophrenia ( 25056061 29483656)	Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		2 interacting genes: IMMT RNF7	40 interacting genes: BTRC CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 UBE2S
Entrez ID		23659	9616
HPRD ID		07128	04840
Ensembl ID		ENSG00000103066	ENSG00000114125
Uniprot IDs		Q8NCC3	Q9UBF6
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW	2ECL
Enriched GO Terms of Interacting Partners?
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