RNF7 and MKRN3

Number of citations of the paper that reports this interaction (PubMedID 22493164)
5

Data Source:
BioGRID (two hybrid)

		RNF7	MKRN3
Description		ring finger protein 7	makorin ring finger protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Nuclear SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Ribonucleoprotein Complex
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	Protein Binding Transferase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein Neddylation Response To Redox State	Protein Ubiquitination
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)	Height ( 31562340) Menarche (age at onset) ( 25231870) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		40 interacting genes: BTRC CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 UBE2S	61 interacting genes: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 GRAP2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 NKAPD1 PEX10 PEX5 POLR1C PRPF31 PSMA1 RBM41 RBPMS RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TLE5 TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W ZNF688
Entrez ID		9616	7681
HPRD ID		04840	04836
Ensembl ID		ENSG00000114125	ENSG00000179455
Uniprot IDs		Q9UBF6	Q13064
PDB IDs		2ECL
Enriched GO Terms of Interacting Partners?
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