RNF7 and UBE2M

Number of citations of the paper that reports this interaction (PubMedID 19250909)
87

Data Source:
BioGRID (pull down)

		RNF7	UBE2M
Description		ring finger protein 7	ubiquitin conjugating enzyme E2 M
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Nuclear SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Nucleoplasm Cytosol
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding NEDD8 Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Protein Neddylation Response To Redox State	Cellular Protein Modification Process Protein Ubiquitination Positive Regulation Of Neuron Apoptotic Process Post-translational Protein Modification Protein Neddylation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	TGF-beta receptor signaling activates SMADs Dectin-1 mediated noncanonical NF-kB signaling NIK - noncanonical NF-kB signaling Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		40 interacting genes: BTRC CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 UBE2S	28 interacting genes: APP CAND1 CBL CPNE1 CPNE2 CPNE4 CUL1 CUL7 DCUN1D1 DCUN1D2 DCUN1D3 DCUN1D4 DCUN1D5 FBXO7 ITCH MARCHF7 NEDD4 NEDD8 PINK1 PRKN RBX1 RNF111 RNF7 SENP8 SMURF1 TERF1 TP53 UBA3
Entrez ID		9616	9040
HPRD ID		04840	04414
Ensembl ID		ENSG00000114125	ENSG00000130725
Uniprot IDs		Q9UBF6	A0A024R4T4 P61081
PDB IDs		2ECL	1TT5 1Y8X 2NVU 3TDU 3TDZ 4GAO 4P5O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?