EDC4 and YTHDC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		EDC4	YTHDC1
Description		enhancer of mRNA decapping 4	YTH domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding	RNA Binding Protein Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay	MRNA Splice Site Selection MRNA Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Schizophrenia ( 25056061 29483656)	Obesity-related traits ( 23251661)
Interacting Genes		5 interacting genes: CCL5 EIF2AK2 FBLN1 GIT2 YTHDC1	35 interacting genes: ABL1 ADAMTS4 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		23644	91746
HPRD ID		06911	11689
Ensembl ID		ENSG00000038358	ENSG00000083896
Uniprot IDs		Q6P2E9	J3QR07 Q96MU7
PDB IDs			2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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