NUP62 and OGT

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		NUP62	OGT
Description		nucleoporin 62	O-linked N-acetylglucosamine (GlcNAc) transferase
Image
GO Annotations	Cellular Component	Spindle Pole Cell Nuclear Envelope Annulate Lamellae Nuclear Pore Nucleoplasm Cytoplasm Centrosome Nuclear Membrane Host Cell Nuclear Pore Central Transport Channel Mitotic Spindle Flemming Body Ribonucleoprotein Complex	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Plasma Membrane Protein N-acetylglucosaminyltransferase Complex Mitochondrial Membrane Protein-containing Complex Cell Projection
	Molecular Function	Chromatin Binding Protein Binding Phospholipid Binding Structural Constituent Of Nuclear Pore Kinesin Binding Receptor Signaling Complex Scaffold Activity Hsp70 Protein Binding SH2 Domain Binding Ubiquitin Binding Protein-containing Complex Binding Thyroid Hormone Receptor Binding PTB Domain Binding Hsp90 Protein Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific) Protein O-GlcNAc Transferase Activity
	Biological Process	Regulation Of Glycolytic Process Transcription, DNA-templated RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Mitotic Metaphase Plate Congression Centrosome Cycle Mitotic Centrosome Separation Cell Surface Receptor Signaling Pathway Spermatogenesis Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Viral Process Protein Sumoylation Viral Transcription Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of Centriole Replication Regulation Of Mitotic Spindle Organization Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Centriole Assembly Regulation Of Cellular Response To Heat Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Protein Localization To Centrosome	Regulation Of Glycolytic Process Regulation Of Gluconeogenesis Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Viral Process Protein Processing Protein Deubiquitination Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K27 Methylation Histone H3-K4 Trimethylation Positive Regulation Of Cold-induced Thermogenesis
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation	HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS
Interacting Genes		76 interacting genes: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 CYTH2 DDX3X DGCR6 DTNB DYNLT1 FABP3 GOPC GORASP2 GTF2E2 HAUS1 HGS HSF2 HSPB11 IDH1 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NAPSA NOSIP NUP153 NUP214 NUP54 NUP58 NUP98 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D SUOX THAP1 TRAF3 TXLNA WASHC3 XPO1 XPO6 ZNF432 ZNF473 ZNF91	22 interacting genes: CSNK2A1 CSNK2B GSK3B HCFC1 HIRA MAPT MTDH NUP62 NUP62CL OGA PHC3 PSG1 SIN3A SNAP91 SP1 SRF TAB1 TAB3 TRAK1 TRAK2 UBC YES1
Entrez ID		23636	8473
HPRD ID		05782	02222
Ensembl ID		ENSG00000213024	ENSG00000147162
Uniprot IDs		A0A024QZF1 P37198	O15294
PDB IDs		2H4D 5IJN 5IJO	1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4CDR 4GYW 4GYY 4GZ3 4GZ5 4GZ6 4N39 4N3A 4N3B 4N3C 4XI9 4XIF 5BNW 5C1D 5HGV 5LVV 5LWV 5NPR 5NPS 5VIE 5VIF 6E37 6EOU 6IBO 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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